Pharma & Specialty Chemical Standards

Darifenacin, a piperidinium derivative, is a selective muscarinic antagonist with the IUPAC name 1-ethyl-4-(2-hydroxy-5-methylphenyl)piperidinium. Its molecular formula is C13H19NO2, molecular weight 221.33 g/mol. Structurally, it contains a piperidine ring linked to a substituted phenyl ring with hydroxyl and methyl groups. Therapeutically, it treats overactive bladder by inhibiting detrusor overactivity. As a quaternary ammonium salt, it exhibits high water solubility and limited lipid permeability. Darifenacin selectively antagonizes M3 muscarinic receptors, reducing acetylcholine-mediated bladder contractions.