💊 Fexofenadine
9 impuritiess available on this parent drug
Fexofenadine, the IUPAC name 4-[[3-[[4-(hydroxydiphenylmethyl)-1-piperidinyl]methyl]-1-piperidinyl]methyl]benzoic acid, is a second-generation H1-antihistamine with molecular formula C32H39NO3 and molecular weight 489.66 g/mol. Structurally, it features a diphenylmethyl group and two piperidine rings, conferring lipophilicity and metabolic stability. Therapeutically, it treats allergic rhinitis and urticaria by selectively blocking peripheral histamine H1 receptors. Its low water solubility (logP ~4.5) and high plasma protein binding (>97%) influence bioavailability. Mechanistically, it competitively inhibits histamine-mediated vasodilation and pruritus without significant central nervous system penetration due to poor blood-brain barrier permeability.
On Request
ABC07893DACAS885946-90-7
MFC32H43NO6
MW537.7
PurityN/A
On Request
ABC07894IDCAS479035-75-1
MFC32H42ClNO5
MW556.1
PurityN/A
On Request
ABC07895YSCASN/A
MFC31H37NO4
MW487.6
PurityN/A
On Request
ABC00703HWCAS76811-98-8
MFC32H37NO4
MW499.6
PurityN/A
On Request
ABC00704YECAS185066-37-9
MFC31H39NO2
MW457.6
PurityN/A
On Request
ABC00705ZTCAS154825-96-4
MFC33H41NO4
MW515.7
PurityN/A
On Request
ABC00707IPCAS115-46-8
MFC18H21NO
MW267.4
PurityN/A
On Request
ABC00706TPCAS1187954-57-9
MFC32H37NO3
MW483.6
PurityN/A
On Request
ABC07896WZCAS153439-40-8
MFC32H40ClNO4
MW538.1
PurityN/A
