(1S,3R,4S)-Ethyl 4-Amino-3-((tert-butoxycarbonyl) amino)cyclohexanecarboxylate Oxalate
(1S,3R,4S)-Ethyl 4-Amino-3-((tert-butoxycarbonyl) amino)cyclohexanecarboxylate Oxalate is a stereospecific cyclohexyl ester bearing a 4-amino group, a Boc-protected 3-amino substituent, and an ethyl ester moiety, stabilized as an oxalate salt. The compound’s chiral centers and protected amino functionality align with intermediate stages of Edoxaban synthesis, where the tert-butoxycarbonyl group acts as a temporary amino-protecting agent. Its structural configuration mirrors the core scaffold of the parent anticoagulant, with the ester and oxalate groups facilitating solubility and stability during synthetic processes. Functions as a critical HPLC reference standard for Edoxaban impurity quantification.
On Request📝 Synonyms
🔬 Chemical Identifiers
CCOC(=O)[C@H]1CC[C@@H]([C@@H](C1)NC(=O)OC(C)(C)C)N.C(=O)(C(=O)O)O
InChI=1S/C14H26N2O4.C2H2O4/c1-5-19-12(17)9-6-7-10(15)11(8-9)16-13(18)20-14(2,3)4;3-1(4)2(5)6/h9-11H,5-8,15H2,1-4H3,(H,16,18);(H,3,4)(H,5,6)/t9-,10-,11+;/m0./s1
XOOSYRSTVVOEEP-PBDVDRNWSA-N
