AHD is a structurally related impurity of Nitrofuran, characterized by a five-membered furan ring substituted with an amino group at the 2-position and a hydroxyl group at the 5-position, alongside a ketone functionality at the 4-position. This compound arises as a synthetic byproduct during the oxidation step of Nitrofuran production, characterized by its ability to form stable crystalline complexes with metal ions. It serves as a critical HPLC reference standard for quantifying process-related impurities in Nitrofuran drug substances.
On RequestC1C(=O)NC(=O)N1N
InChI=1S/C3H5N3O2/c4-6-1-2(7)5-3(6)8/h1,4H2,(H,5,7,8)
KVYKDNGUEZRPGJ-UHFFFAOYSA-N