Boc Baclofen
Boc Baclofen is a tert-butyloxycarbonyl-protected derivative of baclofen, featuring a gamma-aminobutyric acid (GABA) backbone substituted with a 4-chlorophenyl group. The Boc (t-BOC) moiety, a tertiary butyl ester of carbamic acid, sterically shields the primary amine, rendering it chemically inert during synthetic processes. This structural modification disrupts the parent drug’s pharmacophore while preserving its core scaffold. The compound arises as an intermediate in the synthesis of baclofen, where the protecting group is selectively removed to restore bioactivity. It serves as an HPLC reference standard for quantifying residual amine-protected species in drug substance impurity profiling.
On Request
Molecular Formula
C15H20ClNO4
Molecular Weight
313.7700
CAS Number
78131-30-3
✓ Verified
PubChem CID
13100840 ↗
IUPAC Name
3-(4-chlorophenyl)-4-[(2-methylpropan-2-yl)oxycarbonylamino]butanoic acid
Also Search Other Suppliers
📝 Synonyms
78131-30-3
4-(tert-Butoxycarbonylamino)-3-(4-chlorophenyl)butanoic acid
4-{[(tert-butoxy)carbonyl]amino}-3-(4-chlorophenyl)butanoic acid
MFCD09909485
3-(4-chlorophenyl)-4-[(2-methylpropan-2-yl)oxycarbonylamino]butanoic acid
SCHEMBL1998566
CKEIMCIEKVQSSN-UHFFFAOYSA-N
4-((tert-Butoxycarbonyl)amino)-3-(4-chlorophenyl)butanoic acid
DA-41368
EN300-200635
🔬 Chemical Identifiers
CC(C)(C)OC(=O)NCC(CC(=O)O)C1=CC=C(C=C1)Cl
InChI=1S/C15H20ClNO4/c1-15(2,3)21-14(20)17-9-11(8-13(18)19)10-4-6-12(16)7-5-10/h4-7,11H,8-9H2,1-3H3,(H,17,20)(H,18,19)
CKEIMCIEKVQSSN-UHFFFAOYSA-N
Quick enquiry on WhatsApp:
Ask about this product →
