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Bupropion USP Related Compound D

Bupropion USP Related Compound D is a structurally related impurity derived from the synthetic pathway of bupropion hydrochloride. It features a substituted cyclohexane ring fused to a naphthalene core, with a chlorine atom appended at the 3-position of the aromatic system and a tertiary amine moiety. This compound arises as a side product during chlorination steps in bupropion synthesis, differing from the parent drug by a single chlorine substitution and hydrogenation state. Its distinct electronic and steric properties enable its use as an HPLC reference standard for impurity profiling in bupropion APIs.

On Request
Molecular Formula C13H20ClNO
Molecular Weight 241.7600
CAS Number 63199-74-6 ✓ Verified
PubChem CID 3047298 ↗
Purity N/A
Product Type API Impurity
Parent Drug Bupropion
Lead Time On Request
IUPAC Name 2-(tert-butylamino)-1-phenylpropan-1-one;hydrochloride
Official Reference Standards
Std Catalog # Quantity Price
USP 1A08410 ↗ 25 mg USD 1100.00

📝 Synonyms

63199-74-6 2-(tert-Butylamino)propiophenone Hydrochloride F4215L598Y 1-Propanone, 2-((1,1-dimethylethyl)amino)-1-phenyl-, hydrochloride RefChem:1062067 Deschloro Bupropion Hydrochloride Deschloro Bupropion-d9 Hydrochloride 2-(tert-butylamino)-1-phenylpropan-1-one;hydrochloride 2-((1,1-Dimethylethyl)amino)-1-phenyl-1-propanone hydrochloride 2-[(1,1-Dimethylethyl)amino]-1-phenyl-1-propanone Hydrochloride

🔬 Chemical Identifiers

CC(C(=O)C1=CC=CC=C1)NC(C)(C)C.Cl
InChI=1S/C13H19NO.ClH/c1-10(14-13(2,3)4)12(15)11-8-6-5-7-9-11;/h5-10,14H,1-4H3;1H
OXZBSTLIANDWJA-UHFFFAOYSA-N
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