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Medroxyprogesterone

Medroxyprogesterone is a synthetic progestin derived from progesterone via 6α-methylation and 17α-hydroxylation, featuring a 3-oxo-Δ4-pregnene core with a 17-hydroxyl group and a 6-methyl substituent. The compound exhibits enhanced metabolic stability relative to progesterone due to steric hindrance at C6 and hydrogen bonding capacity at C17. Its polarity is modulated by the hydroxyl group, enabling lipid-soluble delivery. It functions as an active pharmaceutical ingredient in the formulation of progestin-based therapeutic agents.

On Request
Molecular Formula C22H32O3
Molecular Weight 344.5000
CAS Number 520-85-4 ✓ Verified
PubChem CID 10631 ↗
Purity N/A
Product Type API
Lead Time On Request
IUPAC Name (6S,8R,9S,10R,13S,14S,17R)-17-acetyl-17-hydroxy-6,10,13-trimethyl-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-3-one
Official Reference Standards
Std Catalog # Quantity Price
USP 1378023 ↗ 25 mg USD 948.00

📝 Synonyms

medroxyprogesterone 520-85-4 Medroxyprogesteron Medroxiprogesterona Medroxyprogesteronum Medrossiprogesterone 17-Hydroxy-6alpha-methylprogesterone 6alpha-Methyl-17alpha-hydroxyprogesterone 17alpha-Hydroxy-6alpha-methylprogesterone 6alpha-Methyl-4-pregnen-17alpha-ol-3,20-dione

🔬 Chemical Identifiers

C[C@H]1C[C@@H]2[C@H](CC[C@]3([C@H]2CC[C@@]3(C(=O)C)O)C)[C@@]4(C1=CC(=O)CC4)C
InChI=1S/C22H32O3/c1-13-11-16-17(20(3)8-5-15(24)12-19(13)20)6-9-21(4)18(16)7-10-22(21,25)14(2)23/h12-13,16-18,25H,5-11H2,1-4H3/t13-,16+,17-,18-,20+,21-,22-/m0/s1
FRQMUZJSZHZSGN-HBNHAYAOSA-N
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