Propranolol HCl impurity C
Propranolol HCl impurity C is a dimeric byproduct formed via coupling of two Propranolol molecules through an ether linkage at their 4-hydroxyl groups, resulting in a bis-ether structure with an extended aromatic naphthyl core. The compound retains the isopropylamine side chain of the parent drug but features an additional oxygen bridge connecting the dimeric units. This impurity arises during synthetic oxidation steps and serves as an HPLC reference standard for monitoring process consistency in Propranolol formulations.
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Molecular Formula
C23H20O3
Molecular Weight
344.4000
CAS Number
17216-10-3
⚠ Unverified
PubChem CID
603039 ↗
IUPAC Name
1,3-dinaphthalen-1-yloxypropan-2-ol
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Official Reference Standards
| Std | Catalog # | Quantity | Price |
|---|---|---|---|
| USP | 1A18340 ↗ | 25 mg | USD 530.00 |
📝 Synonyms
1,3-Bis(1-naphthalenyloxy)-2-propanol
2-Propanol, 1,3-bis(1-naphthalenyloxy)-
1,3-Bis(1-naphthoxy)-2-propanol
1,3-BIS(NAPHTHALEN-1-YLOXY)PROPAN-2-OL
Bis-ether derivative
HC9MT748YY
2-Propanol, 1,3-bis(1-naphthyloxy)-
1,3-Bis(naphthalen-1-yloxy)propane-2-ol
DTXSID50345256
Propranolol hydrochloride impurity C [EP]
🔬 Chemical Identifiers
C1=CC=C2C(=C1)C=CC=C2OCC(COC3=CC=CC4=CC=CC=C43)O
InChI=1S/C23H20O3/c24-19(15-25-22-13-5-9-17-7-1-3-11-20(17)22)16-26-23-14-6-10-18-8-2-4-12-21(18)23/h1-14,19,24H,15-16H2
PKZXCEVVANTTGF-UHFFFAOYSA-N
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