Simvastatin
Simvastatin is a lactone prodrug featuring a pyrrole-fused hexahydrophthalide core with a 2-methylbutyryl side chain. Its structure includes a γ-lactone ring and a 1-pyrroline moiety, which undergo enzymatic hydrolysis to yield the active hydroxy acid metabolite. The molecule's conjugated double bond system and ester functionality contribute to its pharmacokinetic profile. As the parent drug, it serves as the HPLC reference standard for quantifying statin derivatives in pharmaceutical formulations.
On Request
Molecular Formula
C25H38O5
Molecular Weight
418.6000
CAS Number
79902-63-9
✓ Verified
PubChem CID
54454 ↗
IUPAC Name
[(1S,3R,7S,8S,8aR)-8-[2-[(2R,4R)-4-hydroxy-6-oxooxan-2-yl]ethyl]-3,7-dimethyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl] 2,2-dimethylbutanoate
Also Search Other Suppliers
Official Reference Standards
| Std | Catalog # | Quantity | Price |
|---|---|---|---|
| EP | S0650000 ↗ | 200 MG | EUR 90.00 |
| EP | Y0002069 ↗ | 5 MG | EUR 90.00 |
| USP | 1612700 ↗ | 200 mg | USD 297.00 |
📝 Synonyms
simvastatin
79902-63-9
Zocor
Synvinolin
MK-733
Sinvacor
Denan
Lipex
Simvastatine
Sivastin
🔬 Chemical Identifiers
CCC(C)(C)C(=O)O[C@H]1C[C@H](C=C2[C@H]1[C@H]([C@H](C=C2)C)CC[C@@H]3C[C@H](CC(=O)O3)O)C
InChI=1S/C25H38O5/c1-6-25(4,5)24(28)30-21-12-15(2)11-17-8-7-16(3)20(23(17)21)10-9-19-13-18(26)14-22(27)29-19/h7-8,11,15-16,18-21,23,26H,6,9-10,12-14H2,1-5H3/t15-,16-,18+,19+,20-,21-,23-/m0/s1
RYMZZMVNJRMUDD-HGQWONQESA-N
Quick enquiry on WhatsApp:
Ask about this product →
